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Latest Drugs
Women's Health and Obs/Gyn Drug Data - A-Z (Espanol)
Drug Class Description
Anticonceptivos localesDrug Description
OVULOSPresentation
Anticoncepción (intravaginal): Ovulos/supositorios/comprimidos: Introducir profundamente en la vagina 1 óvulo/supositorio/comprimido 10 minutos como mínimo y una hora como máximo, antes de cada repetición del coito. Introducido el óvulo, hay que permanecer 7-8 minutos en posición de decúbito supino a fin de facilitar su fusión. Aunque la duración del efecto persiste aproximadamente una hora y media, cada repetición del coito precisa de un nuevo óvulo, comprimido o supositorio, independientemente del tiempo que transcurra entre cada coito. Espuma vaginal: 1 aplicador lleno de espuma justo antes, y no más de una hora antes, de cada repetición del coito. Esponja vaginal: 1 esponja introducida en la vagina a menos de 24 horas antes coito. Antes de la aplicación debe humedecerse la esponja completamente con agua limpia para activar el espermicida. La esponja debe doblarse por la mitad antes de su introducción. Proporciona protección durante 24 h. En caso de repetición del coito no es necesario utilizar otra si no han transcurrido más de 24 h, mientras se haya dejado un mínimo de 6 horas después del coito. Debe dejarse puesta en la vagina un mínimo de 6 h y un máximo de 30 h. Su actividad no disminuye al ducharse, bañarse o nadar. Cada esponja sólo debe utilizarse una vez. Si se expulsa en las 6 horas siguientes al coito, se debe introducir de inmediato otra nueva, previamente humedecida. - Especificaciones para la administración del medicamento: Insertar profundamente en la vagina.Indications
Autorizadas en España: Anticoncepción local.Interactions
La eficacia de este medicamento puede ser reducida por los detergentes aniónicos (ej: jabones). Para ello, antes de cada aplicación hay que eliminar los indicios de jabón que puedan existir procedentes de lavados previos.Adverse Reactions
Las reacciones adversas más características son: -Ocasionalmente (1-9%): reacciones alérgicas: prurito vaginal e irritación local. -Excepcionalmente (<<1%): se ha notificado algún caso de síndrome del shock tóxico con el uso de las esponjas impregnadas de espermicidas: vómitos, mareos, fiebre, diarrea, mialgia y erupciones exantemáticas similares a una quemadura solar.Manufacturer
ABELLODrug Availability
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Related News
Study backs findings that some newer contraceptive pills more likely to cause VTE Women's Health and Obs/Gyn Page
A new study confirms earlier findings that certain oral contraceptive pills including those with desogestrel, gestodene, or drospirenone, including Safyral, from Bayer HealthCare, are more likely to cause serious blood clots (venous thromboembolism - VTE ) than others. The authors, led by Dr Øjvind Lidegaard from the University of Copenhagen, say that women on pills containing one of the newer types of progestogen hormone (drospirenone, desogestrel or gestodene) have double the risk of VTE than women on pills containing an older progestogen (levonorgestrel). The researchers reviewed data of the hormonal contraception patterns and first time VTE episodes for all Danish non-pregnant women between the ages of 15 and 49 from January 2001 until December 2009. Though the relative risk of VTE whilst taking the oral contraceptive pill is still low, compared with non-users of hormonal contraception, pills with levonorgestrel increase the risk of VTE threefold and pills with drospirenone, desogestrel or gestodene increase the risk sixfold. In absolute terms, the risk of VTE in current users of newer pills is about 10 per 10,000 women years. See: "Risk of venous thromboembolism from use of oral contraceptives containing different progestogens and oestrogen doses: Danish cohort study, 2001-9" Øjvind Lidegaard et al. British Medical Journal 2011;343:d6423 doi: 10.1136/bmj.d6423
Contraceptives containing Beyaz (Bayer Healthcare) show higher risk of blood clots Women's Health and Obs/Gyn Page
The use of oral Contraceptive pills that contain Beyaz (drospirenone), from Bayer Healthcare, is linked to a significantly higher risk of blood clots, both deep vein thrombosis and pulmonary embolism, according to an article in the Canadian Medical Association Journal. The study found that the use of Beyz-containing combined oral contraceptives was associated with a significantly increased risk of venous thrombotic events (deep vein thrombosis and pulmonary embolism) but not arterial thrombotic events (transient ischemic attack and cerebrovascular accident), relative to use of second- or third-generation combined oral contraceptives. Risk was highest in the early months of use. Older age, high blood pressure, high cholesterol, cancer and obesity were also risk factors for blood clots. The FDA will discuss the risks and benefits of these contraceptives at a meeting of the Reproductive Health Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee on Dec. 8, 2011. See: "Higher risk of venous thrombosis associated with drospirenone-containing oral contraceptives: a population-based cohort study" Naomi Gronich, Idit Lavi, Gad Rennert. CMAJ November 7, 2011 First published November 7, 2011, doi: 10.1503/cmaj.110463
Nomac/E2 is rejected by FDA as a contraceptive Women's Health and Obs/Gyn Page
Zoely/Nomac/E2 is a combined contraceptive pill (nomegestrol acetate (a progestogen) and estradiol (an oestrogen) which was approved by EMA for Teva Pharma on 17 July 2011 to be launched by year end and rejected by the FDA for Merck Inc. some days ago.
