Updated: 17 Aug 2009
For the treatment of mild to moderate pain. Suitable for migraine, headache, rheumatic pain, period pain, toothache, neuralgia, sore throats and feverishness and the symptomatic relief of colds and influenza.
Analgesic, Antipyretic and mild Anti-Inflammatory
Paracetamol 500 mg per tablet Caffeine 30 mg per tablet Codeine Phosphate 8 mg per tablet Film-coated tablet.
Paracetamol, Caffeine and Codeine Phosphate
White, capsule-shaped tablet with dimensions of 17.55 mm x 7.5 mm and debossed on one face to read PCC.
Chefaro UK Ltd
For oral administration only.
Adults, the Elderly and Children over 12 years of age:
2 tablets taken with water every 4-6 hours
No more than 8 tablets in 24 hours
Do not give to children under 12 years of age.
Do not take for more than 3 days without consulting a doctor.
Children over 12 years of age: 2 tablets taken with water every 4-6 hours No more than 8 tablets in 24 hours Do not give to children under 12 years of age. Do not take for more than 3 days without consulting a doctor
See Adult Dosage
Care is advised in the administration of paracetamol to patients with severe renal or severe hepatic impairment. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease.
Care should be taken in administering the product to any patient whose condition may be exacerbated by opioids, particularly the elderly, in whom there is increased sensitivity to the central and gastro-intestinal effects, those on concurrent treatment with other CNS depressant drugs, those with prostatic hypertrophy and those with inflammatory or obstructive bowel disorders.
Patients should be advised not to exceed the recommended dose.
Patients should be advised not to take other paracetamol-containing products concurrently.
If symptoms persist, patients should consult a doctor.
Keep out of the reach and sight of children.
Adverse effects of paracetamol are rare, but hypersensitivity including skin rash may occur. There have been a few reports of blood dyscrasias including thrombocytopenia and agranulocytosis, but these were not necessarily causally related to paracetamol.
Codeine can produce constipation and drowsiness. Occasional effects are nausea, vomiting, sweating, facial flushing, dry mouth, blurred or double vision, dizziness, postural hypotension, headache, vertigo, palpitations, allergic reactions (itch, skin rash, facial oedema), and difficulties in micturition (dysuria, increased frequency, decrease in amount). Side-effects which occur rarely include hallucinations, nightmares, restlessness and stomach cramps. The frequency and severity are determined by dosage, duration of treatment and individual sensitivity and are unlikely at this dosage. Tolerance and dependency can occur, especially with prolonged high doses of codeine.
High doses of caffeine may produce headache, tremor, nervousness and irritability.
Hypersensitivity to paracetamol, caffeine, codeine or any of the other constituents. Conditions where morphine and opioids are contraindicated, eg acute asthma, respiratory depression, acute alcoholism, head injuries, raised intra-cranial pressure and following biliary tract surgery.