Updated: 11 May 2009
Prophylaxis of angina.
White scored tablets marked E10, E20 or E40.
Isosorbide mononitrate - angina
Tablets, isosorbide mononitrate 10 mg , 20 mg , 40 mg .
Initially, 10 mg twice daily.
Maintenance, usually 40-80 mg daily in two or three divided doses after meals; maximum 120mg daily.
Use with caution in hypothyroidism, hypothermia, malnutrition, severe liver or renal disease. Pregnacy and lactation.
Headache, flushes, dizziness.
Known sensitivity to nitrates. Acute myocardial infarction with low filling pressure, acute circulatory failure (shock, vascular collapse), or very low blood pressure. Avoid in patients with marked anaemia, head trauma, cerebral haemorrhage, severe hypotension, hypovolaemia.