11 Jan 2013

Dihydrocodeine Tablets (dihydrocodeine tartrate) - United Kingdom

Updated: 11 Jan 2013

Dihydrocodeine Tablets BP 30mg

As an analgesic for the relief of moderate to severe pain. Dihydrocodeine Tablets 30mg are indicated in all painful conditions where an alert patient is desired, eg sciatica, osteo-arthritis, chronic rheumatoid arthritis, arthritis of the spine, peripheral vascular disease, post-herpetic neuralgia, Paget's disease, malignant disease, post-operative pain.

Because dihydrocodeine, in the recommended doses, causes little or no respiratory depression, its use in the treatment of post-operative pain may reduce the risk of chest complications.

Dihydrocodeine Tablets Description, Presentation and Dosage

Dihydrocodeine Tablets Description

Dihydrocodeine Tablets Drug Class Description

Dihydrocodeine ; Belongs to the class of natural opium alkaloids. Analgesic - ATC Code: N02AA08

Dihydrocodeine Tablets Drug Description

Each tablet contains 30mg Dihydrocodeine Tartrate.

Dihydrocodeine Tablets Generic Name

dihydrocodeine tartrate

Dihydrocodeine Tablets Presentation

Dihydrocodeine Tablets Presentation

White uncoated tablets.

Free Medical Education Resources

Dihydrocodeine Tablets Dosage

Dihydrocodeine Tablets Adult Dosage

The analgesic effect is not materially enhanced by increasing the dose above that recommended below; in severe cases the interval between doses should be reduced to obtain the requisite analgesic cover.

It is recommended that this product should be taken during or after food.

Adults: 1 tablet every four to six hours or at the discretion of the practitioner.

Children under 12 years: A more suitable dosage form is recommended for this age group (e.g. elixir).

Elderly: Dosage should be reduced in the elderly.

For oral use.

Dihydrocodeine Tablets Precautions, Reactions and Contraindications

Dihydrocodeine Tablets Special Precautions

Dihydrocodeine Tablets Special Precautions

Dihydrocodeine should be given in reduced doses or with caution to patients with asthma and decreased respiratory reserve. Avoid use during an acute asthma attack.

Dihydrocodeine should be avoided, or the dose reduced in patients with hepatic or renal impairment.

Dihydrocodeine should be given in reduced doses or with caution to;

debiltated patients, adrenocortical insuffciency, prostatic hyperplasia, urethral stricture,hypotension, shock, inflammatory or obstructive bowel disorders, hypothyroidism orconvulsive disorders.

However, these conditions should not necessarily be a deterrent to use in palliative care.

Use in caution in those with a history of drug abuse.

Alcohol should be avoided whilst under treatment with dihydrocodeine.

Contains lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp lactose deficiency or glucose-galactose malabsorption should not take this medicine.

The risk-benefit of continued use should be assessed regularly by the prescriber.

The leaflet will state in a prominent position in the 'before taking' section:

• Do not take for longer than directed by your prescriber.

• Taking dihydrocodeine regularly for a long time can lead to addiction, which might cause you to feel restless and irritable when you stop the tablets.

• Taking a pain killer for headaches too often or for too long can make them worse.

The label will state (To be displayed prominently on outer pack – not boxed):

• Do not take for longer than directed by your prescriber as taking dihydrocodeine regularly for a long time can lead to addiction.

Dihydrocodeine Tablets Adverse Reactions

Dihydrocodeine Tablets Adverse Reactions

Skin disorders; rash, urticaria, pruritius, sweating.

Central and peripheral nervous system disorders; paraesthesia, dizziness, headache, vertigo, respiratory depression. Muscle rigidity has been reported after high doses.

Vision disorders; visual disturbances, miosis.

Psychiatric disorders; drowsiness, changes of mood, confusion, sexual dysfunction, hallucinations, euphoria.

Gastro-intestinal system disorders; dry mouth, nausea, vomiting, abdominal pain, constipation.

Liver and biliary system disorders; biliary spasm which may be associated with alterations in liver enzyme values.

Cardiovascular disorders general; hypotension.

Heart rate and rhythm disorders; bradycardia, tachycardia, palpitations.

Vascular (extracardiac) disorders; facial flushing.

Urinary systems disorders; Micturition may be difficult and there may be ureteric spasm.

Body as a whole, general; oedema.

• Regular prolonged use of dihydrocodeine is known to lead to addiction and tolerance. Symptoms of restlessness and irritability may result when treatment is then stopped.

• Prolonged use of a painkiller for headaches can make them worse.

Dihydrocodeine Tablets Contraindications

Dihydrocodeine Tablets Contraindications

• Hypersensitivity to dihydrocodeine or any of the excipients

• Respiratory depression

• Obstructive airways disease

• Acute alcoholism

• Risk of paralytic ileus

• Head injuries or conditions in which intracranial pressure is raised.

Related Drugs - Pain Management

Back to top