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Latest Drugs
Nutrition and Dietetics Drug Data - A-Z (English)
Drug Class Description
Vitamin B (B12 vitamins).Generic Name
CyanocobalaminDrug Description
Cytacon Tablets: White f- c tablets marked CYTACON. Cytacon Liquid: Syrup.Presentation
Cytacon Tablets, cyanocobalamin 50 microgram . Cytacon Liquid, cyanocobalamin 35 micrograms per 5mL. Cytacon is not prescribable on the NHS. Only available at NHS expense for treatment or prevention of vitamin B deficiency in a patient who is 12 vegan or who has a proven vitamin B deficiency of dietary origin; prescription must be endorsed 12 'SLS'.Indications
Post-gastrectomy vitamin B deficiency, nutritional vitamin 12 B deficiency, tropical sprue. Pernicious anaemia if 12 intramuscular route unacceptable.Adult Dosage
Tablets: 1 - 3 tablets daily. Pernicious anaemia, at least 6 daily.
Liquid: 5 - 10mL two or three times daily. Pernicious anaemia, at least 300 microgram daily.
Child Dosage
Tablets: 1 tablet daily. Liquid: 5mL two or three times daily.Contra Indications
Hypersensitivity to the product.Special Precautions
Pernicious anaemia - must use adequate dose and blood picture must be examined regularly at least every three months for 18 months until stabilised and then annually. Long term treatment with Cytacon liquid may increase risk of dental caries. Administer liquid with care in diabetes mellitus (contains sugar).
Interactions
Para-aminosalicylic acid, methyldopa, colchicine, biguanides, neomycin, colestyramine (cholestyramine), pot. chlor., cimetidine.
Adverse Reactions
Rare hypersensitivity reactions.Manufacturer
GoldshieldDrug Availability
(P)Updated
06 May 2009Advert for Healthcare Professionals Only
Latest News
12th February 2012
Cyberknife (Accuray Inc) relieves pain of Trigeminal Neuralgia facial nerve condition Page
Cyberknife, the Intensity Modulated RadioTherapy system from Accuray Inc, can relieve the stabbing pain of the facial nerve condition Trigeminal Neuralgia. Researchers treated 17 patients with Trigeminal Neuralgia with Cyberknife radiosurgery between 2007 and 2009. The patients, who were aged between 36 and 90, had had their symptoms for between one and 11 years and had not responded to the available treatment options. The researchers zapped a 6mm length of trigeminal nerve, just 2 to 3mm from the root, using a maximum radiation dose of 73.06 Gy. The patients were then monitored regularly after the procedure, for an average of just under 12 months. Complete data were available for 16 patients, 14 of whom obtained either partial or complete relief from their symptoms. The average time before symptom relief occurred was just under two months, but varied from three weeks to six months. Four patients relapsed after the procedure, between three and 18 months later. No patient experienced major complications as a result of the procedure, and only two patients reported any sensory side effects. See: >"Cyberknife radiosurgery in treating trigeminal neuralgia" by Bryan M Lazzara et al. Journal of NeuroInterventional Surgery (2012). doi:10.1136/neurintsurg-2011-010125
FDA approves trial of Celution System (Cytori Therapeutics) for CMI Cardiology Page
Cytori Therapeutics has received an Investigational Device Exemption (IDE) approval from the FDA to begin the ATHENA trial using its Celution System. ATHENA will investigate the use of the Celution System to treat a form of Coronary Heart Disease, Chronic Myocardial Ischemia (CMI). The IDE application was originally submitted to the FDA in December 2011. The trial will enroll up to 45 patients with no-option CMI who have limited therapeutic options. It will evaluate a variety of clinical and functional outcomes, including safety, peak oxygen consumption (mVO2), and clinical outcomes at 12-months.
Phase III Trial of MDV 3100 (Medivation/Astellas) in Prostate Cancer patients shows positive results Oncology Page
Researchers have presented positive results on all efficacy endpoints from the Phase III AFFIRM trial of the investigational drug MDV 3100, from Medivation and Astellas, in men with Prostate Cancer previously treated with chemotherapy. The results, presented at the 2012 Genitourinary Cancers Symposium, show that men taking MDV 3100 lived for a median of 18.4 months, compared with 13.6 months for men taking placebo. MDV 3100 also met all secondary endpoints, including radiographic progression-free survival (8.3 versus 2.9 months; PSA declines of 50% or greater were more common in the MDV 3100 group than in the placebo group (54.0% versus 1.5%; and MDV 3100 was found to be well tolerated. The data was presented by Howard I. Scher, chief, Genitourinary Oncology Service at Memorial-Sloan Kettering Cancer Center.
