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Allergy and Clinical Immunology Drug Data - A-Z (English)
Drug Class Description
Hydrating agents / keratolytics.Generic Name
Urea, lactic acidDrug Description
A white cream containing Urea Ph.Eur 10.0 % w/w and Lactic Acid Ph.Eur 5.0% w/w in a stabilising emulsified base.Presentation
Cream for topical (cutaneous) useIndications
To be applied topically for the correction of hyperkeratosis and dryness in ichthyosis and allied conditions characterised by dry, rough, scaly skin.Adult Dosage
For external use only.
Dosage and administration:
Adults, elderly and children:
A thick layer of Calmurid is applied twice daily after washing the affected area. The cream is left on the skin for 3-5 minutes and then rubbed lightly in. Excess cream should be wiped off the skin with a tissue, not washed off. Frequency of application can be reduced as the patient progresses. In hyperkeratosis of the feet apply Calmurid as above after soaking the feet in warm water for 15 minutes and drying with a rough towel.
Contra Indications
Hypersensitivity to any constituent of the product.
Special Precautions
Calmurid is acidic and hypertonic and can cause smarting if applied to raw areas, fissures or mucous membranes. Where this is a barrier to therapy the use of Calmurid diluted 50% with aqueous cream B.P. for one week should result in freedom from smarting upon use of Calmurid.
Interactions
Low pH of cream might affect stability of other drugs.
Adverse Reactions
Calmurid is acidic and hypertonic and can cause smarting if applied to raw areas, fissures or mucous membranes.
Manufacturer
GaldermaDrug Availability
(P)Updated
15 April 2009Advert for Healthcare Professionals Only
Related News
Study finds benefits of Xolair for Allergic Asthma treatment Allergy and Clinical Immunology Page
New results from the APEX trial of Xolair (omalizumab), from Novartis, show that the drug considerably reduces patients need for steroid use, while at the same time helping disease control and lowering the amount of Asthma exacerbations. Usual treatment for Allergic Astham is oral steroids, but these are associated with weight gain, hypertension, osteoporosis and depression. The data, presented at the 2011 European Respiratory Society congress, shows that in the 12 months after patients started on Xolair (p<0.001), the mean total dose of oral corticosteroids per individual reduced by 34%, with 49% of individuals stopping the oral steroids altogether and 64% considerably reducing their oral corticosteroid dosage. Compared to the previous year, patients experienced a considerable reduction in the amount of asthma exacerbations after 12 months of treatment (53%, 1.7 versus 3.7, 95% CI, p<0.001). Lung function was also found to improve.
