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Latest Drugs
Generic Name
prochlorperazine maleateDrug Description
Each buccal tablet contains 3.0 mg prochlorperazine maleate BP.Presentation
Buccal tabletIndications
Symptomatic treatment of vertigo due to Ménière's Disease, Labyrinthitis and other causes. For nausea and vomiting from whatever cause. In the treatment of migraine.
Adult Dosage
To be placed in the buccal cavity.
Adults and children aged 12 years and over: One or two Buccastem 3 mg Tablets twice a day.
Children under 12 years: Not recommended.
Elderly patients: There is no evidence that dosage need be modified for the elderly.
Contra Indications
Buccastem 3 mg is contraindicated in patients with impaired liver function, existing blood dyscrasias, epilepsy, Parkinsons Disease, prostatic hypertrophy, narrow angle glaucoma and known hypersensitivity to the active ingredient.
Special Precautions
Hypotension, usually postural, may occur, particularly in elderly or volume depleted patients. Tardive dyskinesia may occur occasionally, although this is normally associated with higher doses than are recommended for Buccastem 3 mg. Nausea and vomiting as a sign of organic disease may be masked by the anti-emetic action of Buccastem 3 mg.
Interactions
Alcohol and CNS depressants should be used with caution as should α-adrenoreceptor blocking antihypertensives.
Adverse Reactions
Drowsiness, dizziness, dry mouth, insomnia, agitation and mild skin reactions may occur. Extrapyramidal reactions are very unlikely at the recommended dosage. Other effects which have occurred rarely with prochlorperazine and other phenothiazine neuroleptics include jaundice, blood dyscrasias and, very rarely, hyperprolactinaemic effects such as gynaecomastia. Neuroleptic malignant syndrome (hyperthermia, rigidity, autonomic dysfunction and altered consciousness) may occur with any neuroleptic. Use of Buccastem 3 mg tablets may occasionally result in local irritation to the gum and mouth.
Manufacturer
Alliance PharmaceuticalsDrug Availability
POM – Prescription Only MedicineUpdated
22 November 2011Advert for Healthcare Professionals Only
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