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Allergy and Clinical Immunology Drug Data - A-Z (English)
Drug Class Description
Macrolides / keratolytics.Generic Name
Erythromycin, benzoyl peroxideDrug Description
Gel.Presentation
Benzoyl Peroxide, hydrous, equivalent to benzoyl peroxide 5% w/w. Erythromycin 3% w/w.Indications
For the topical treatment of acne vulgaris.Adult Dosage
Benzamycin Gel should be applied twice daily, morning and evening, to areas usually affected by acne or as directed by the physician. These areas should first be gently washed, rinsed with lukewarm water, and gently patted dry. Benzamycin should be applied in a thin layer with the fingertips until dry and the hands washed after application.
It is not recommended for children.
Contra Indications
Benzamycin is contraindicated in persons who have shown hypersensitivity to benzoyl peroxide, erythromycin or any of the other ingredients.
Special Precautions
For external use only. Keep away from the eyes, nose, mouth and other mucous membranes. Very fair skinned individuals should begin with a single application at bedtime allowing overnight medication.
May bleach hair or dyed fabrics.
Interactions
Concomitant topical acne therapy should be used with caution to avoid a possible cumulative irritancy effect. Antagonism has been demonstrated between clindamycin and erythromycin.
Adverse Reactions
Reported adverse reactions have been dryness of the skin, urticaria and face oedema.
Manufacturer
UCB Pharma LimitedDrug Availability
(POM)Updated
09 April 2009Advert for Healthcare Professionals Only
Related News
Study finds benefits of Xolair for Allergic Asthma treatment Allergy and Clinical Immunology Page
New results from the APEX trial of Xolair (omalizumab), from Novartis, show that the drug considerably reduces patients need for steroid use, while at the same time helping disease control and lowering the amount of Asthma exacerbations. Usual treatment for Allergic Astham is oral steroids, but these are associated with weight gain, hypertension, osteoporosis and depression. The data, presented at the 2011 European Respiratory Society congress, shows that in the 12 months after patients started on Xolair (p<0.001), the mean total dose of oral corticosteroids per individual reduced by 34%, with 49% of individuals stopping the oral steroids altogether and 64% considerably reducing their oral corticosteroid dosage. Compared to the previous year, patients experienced a considerable reduction in the amount of asthma exacerbations after 12 months of treatment (53%, 1.7 versus 3.7, 95% CI, p<0.001). Lung function was also found to improve.
