Advert for Healthcare Professionals Only

I am a patient (Please go to our patient website)

Disease Topics
eCME
Webcasts
Knowledge Centres
Latest Drug Updates
Quick Search
All Drug Databases

Advert for Healthcare Professionals Only

Cardiology Drug Data - A-Z (English)

Drug Class Description

Antiplatelets (antiplatelet agents, salicylates).

Generic Name

Aspirin

Drug Description

Each tablet contains: Aspirin BP 75 mg

Presentation

Tablets

Indications

For the secondary prevention of thrombotic cerebrovascular or cardiovascular disease and following by-pass surgery. The advice of a doctor should be sought before commencing therapy for the first time.

Adult Dosage

The usual dosage, for long-term use, is 75mg - 150mg once daily. In some circumstances a higher dose may be appropriate, especially in short-term, and up to 300mg a day may be used on the advice of a doctor.

Child Dosage

Do not give to children aged under 16 years, unless specifically indicated (e.g. for Kawasaki's disease).

Elderly Dosage

The risk/benefit ratios in the elderly have not been fully established

Contra Indications

Active or history of peptic ulceration, haemophilia and other bleeding disorders, hypersensitivity to aspirin.

Special Precautions

Aspirin may induce gastro-intestinal haemorrhage, occasionally major. Patients with hypertension should be carefully monitored.

There is a possible association between aspirin and Reye's syndrome when given to children. Reye's syndrome is a very rare disease, which affects the brain and liver, and can be fatal. For this reason aspirin should not be given to children aged under 16 years unless specifically indicated (e.g. for Kawasaki's disease).

Interactions

Aspirin may enhance the effects of anticoagulants and may inhibit the action of uricosurics.

Experimental data suggest that ibuprofen may inhibit the effect of low dose aspirin on platelet aggregation when they are dosed concomitantly. However, the limitations of these data and the uncertainties regarding extrapolation of ex-vivo data to the clinical situation imply that no firm conclusions can be made for regular ibuprofen use, and no clinically relevant effect is considered to be likely for occasional ibuprofen use

Adverse Reactions

Aspirin may enhance the effects of anticoagulants and may inhibit the action of uricosurics. Aspirin may precipitate bronchospasm and may induce attacks of asthma in susceptible subjects. Hypersensitivity reactions have been reported in susceptible individuals.

Manufacturer

Bristol-Myers Pharmaceuticals

Drug Availability

(P)

Updated

04 June 2009

Drug Languages: en it fr de es no nl pt se

Forgotten password?

ANGETTES 75