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Latest Drugs
Eye Health and Disorders Drug Data - A-Z (English)
Drug Class Description
Carbonic anhydrase inhibitors.Generic Name
GenericDrug Description
Tablets.Presentation
Tablets, acetazolamide 250mg . Available from Regent Labs.Indications
Glaucoma.Adult Dosage
250mg - 1,000mg daily in divided doses.Child Dosage
Not recommended.Contra Indications
Hepatic disease or insufficiency. Hyponatraemia, hypokalaemia. Adrenocortical insufficiency, hyperchloraemic acidosis, severe renal disease or dysfunction. Chronic closed angle glaucoma. Hypersensitivity to sulphonamides. Pregnancy.Special Precautions
Respiratory acidosis, pulmonary obstruction, emphysema. Diabetes. Monitor fluid, electrolytes, blood. Lactation.Interactions
Folic acid antagonists, hypoglycaemics, oral anticoagulants.Adverse Reactions
GI disturbances including nausea, vomiting, diarrhoea; CNS disturbances including drowsiness, paraesthesia; drowsiness, paraesthesia; hypersensitivity reactions. Blood dycrasias, flushing, thirst, headache, rash.Drug Availability
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Related News
MedImmune and Pfizer collaborate on anti cancer tremelimumab Eye Health and Disorders Page
Pfizer and MedImmune ( a subsidiary of AstraZeneca) will collaborate to develop tremelimumab. The drug was unsuccessful in a Phase III trial for Melanoma but discovery of a biomarker has spurred development and DebioPharm are running a Phase III trial for treatment of Melanoma.The agreement will give MedImmune global rights for cancer indications and Pfizer will retain rights to certain undisclosed combinations.
Luveniq is withdrawn from EMA for chronic non-infectious Uveitis Eye Health and Disorders Page
Lux Biosciences has withdrawn Luveniq (voclosporin oral) from the EMA as a treatment for chronic non-infectious Uveitis following a negative opinion from the CHMP which considered that the benefits of the drug did mnot outweight its risks.
Ocriplasmin for Vitromacular Adhesion is filed at EMA Eye Health and Disorders Page
The European Medicines Agency has accepted for review ocriplasmin (2.5 mg/ml, solution for injection) from Thrombogenics ,for the treatment of symptomatic Vitreomacular Adhesion (VMA) including macular hole. Ocriplasmin's MAA will be evaluated through the EMA's centralised procedure with an official start date of 19 October 2011 and, if approved, the product will gain marketing authorisation for all EU Member States simultaneously. Successful approval will make it the first pharmacological treatment for this indication. The company has kept to its stated time frames for the European filing and in announcing the EMA's acceptance of the MAA, the company once more reiterated its plans for the treatment to be filed with the US FDA by the end of the year
