All Topics

Overview

The EPG website contains 51 major disease topic areas, designed to cater for the demands of busy healthcare professionals. Each disease topic area presents a wide range of related disease and treatment information from reputable sources. Content includes related drug data (in 9 European languages), clinical trial study outcomes, guidelines for treatment, disease and treatments knowledge centres, drug news, journals, multimedia, social media and apps.

The regularly updated disease topic areas can be accessed below or via the collapsible menu at the top of each page of the EPG website.

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Drug News

VANTAGE study shows Vercise DBS (Boston Scientific) demonstrates motor function benefits in Parkinson's Disease

19-06-2013

Patients with Parkinson's disease using the Boston Scientific Corporation Vercise DBS (deep brain stimulation) System showed a significant improvement in motor scores according to interim data from...

Phase III trial shows Ilaris (Novartis) allows discontinuation of corticosterioids in sJIA

19-06-2013

In a Phase III clinical trial of Ilaris (canakinumab), from Novartis, patients (2-19 years of age) with active systemic Juvenile Idiopathic Arthritis (SJIA) received subcutaneous injections (4mg/kg...

PRAC recommends the same cardiovascular precautions for diclofenac as for selective COX-2 inhibitors

19-06-2013

The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has concluded that the effects of the painkiller diclofenac on the heart and circulation when given systemically...

Allergy/Clinical Immunology Drug Data - A-Z

Possible searches include drugs or medicines (by brand, generic ingredient or drug class), diseases, conditions and more.

Drug Lang:

Medical Videos

An Overview of Recent Advances in Head and Neck Surgery
An Overview of Recent Advances in Head and Neck Surgery
HPV Vaccine
HPV Vaccine
An Introduction to Twin-Twin Transfusion Syndrome and Possible Treatments
An Introduction to Twin-Twin Transfusion Syndrome and Possible Treatments
Treatment and Surveillance of Non-Muscle Invasive Bladder Cancer - Part 1
Treatment and Surveillance of Non-Muscle Invasive Bladder Cancer - Part 1
An Introduction to Diagnosing Chronic Kidney Disease
An Introduction to Diagnosing Chronic Kidney Disease
Calcific Tendonitis
Calcific Tendonitis
Heart Transplantation - The Reasons for Transplantation and the Success Rates
Heart Transplantation - The Reasons for Transplantation and the Success Rates
Discussion of Clinical Approach to Lower Back Pain
Discussion of Clinical Approach to Lower Back Pain
What Causes Osteoarthritis? An Informative Animation
What Causes Osteoarthritis? An Informative Animation
Discussion of Systemic Candida and Yeast Infections
Discussion of Systemic Candida and Yeast Infections
An Overview of Brain Surgery and the Current Understanding of Brain Function
An Overview of Brain Surgery and the Current Understanding of Brain Function
What Causes Osteoarthritis? An Informative Animation
What Causes Osteoarthritis? An Informative Animation
Cancer Vaccines- Dr. Kelvin Lee
Cancer Vaccines- Dr. Kelvin Lee
The Benefits of CT Screening for Lung Cancer
The Benefits of CT Screening for Lung Cancer
A Discussion on Neglected Tropical Diseases
A Discussion on Neglected Tropical Diseases
3D Medical Animation - Congestive Heart Failure
3D Medical Animation - Congestive Heart Failure
Pathogen Testing for Bloodstream Infections in At-Risk Populations
Pathogen Testing for Bloodstream Infections in At-Risk Populations
An Animations Explaining the Mechanism by which the HIV Virus works
An Animations Explaining the Mechanism by which the HIV Virus works
Animation: New therapy prevents heart failure
Animation: New therapy prevents heart failure
A Discussion on Depression and Anxiety in Patients with Epilepsy
A Discussion on Depression and Anxiety in Patients with Epilepsy
Treatment and Surveillance of Non-Muscle Invasive Bladder Cancer - Part 2
Treatment and Surveillance of Non-Muscle Invasive Bladder Cancer - Part 2
Purine Salvage Enzyme HGPRT and Gout
Purine Salvage Enzyme HGPRT and Gout
An Animation Explaining the Development of Lymphoma
An Animation Explaining the Development of Lymphoma
Does chronic venous insufficiency play a role in MS pathogenesis? Commentary (CONy 2010)
Does chronic venous insufficiency play a role in MS pathogenesis? Commentary (CONy 2010)
Discussion of Hepatitis C in the UK House of Lords June 2011
Discussion of Hepatitis C in the UK House of Lords June 2011
An Overview of Blood Transfusions
An Overview of Blood Transfusions
Discussion of a Paper on the use of GPI's During Coronary Angioplasty Surgery
Discussion of a Paper on the use of GPI's During Coronary Angioplasty Surgery
A Discussion of Palliative and Hospice Care
A Discussion of Palliative and Hospice Care
A Presentation Detailing Behavioural Modification Treatments for Atopic Dermatitis
A Presentation Detailing Behavioural Modification Treatments for Atopic Dermatitis
The Risk Factors Associated With Sexually Transmitted Diseases
The Risk Factors Associated With Sexually Transmitted Diseases
Achondroplasia
Achondroplasia
A Discussion on Breast Reconstruction Following Mastectomy
A Discussion on Breast Reconstruction Following Mastectomy
Aortic Aneurysm Procedure Using the David Reimplantation Technique
Aortic Aneurysm Procedure Using the David Reimplantation Technique
Anesthesia- Regional Anesthesia & Acute Pain Management
Anesthesia- Regional Anesthesia & Acute Pain Management
DNA Gel Electrophoresis - Making and Running a Gel
DNA Gel Electrophoresis - Making and Running a Gel
Corneal Transplant - The Diseases, Procedures and Success Rates
Corneal Transplant - The Diseases, Procedures and Success Rates
A Discussion Following Research into the Importance of Childhood Vaccinations
A Discussion Following Research into the Importance of Childhood Vaccinations
A Guide to the Coronary Angioplasty Procedure
A Guide to the Coronary Angioplasty Procedure
ADA/EASD Consensus Algorithm for the Treatment of Diabetes Mellitus
ADA/EASD Consensus Algorithm for the Treatment of Diabetes Mellitus
Presentation from the 2010 Trauma Summit in Seattle: Salvaging Severe Pilon Fractures
Presentation from the 2010 Trauma Summit in Seattle: Salvaging Severe Pilon Fractures
A Presentation on the Innovations in Minimal Access Paediatric Surgery
A Presentation on the Innovations in Minimal Access Paediatric Surgery
Ocular Histoplasmosis
Ocular Histoplasmosis
An Animation Demonstrating the Role of Natural Killer Cells
An Animation Demonstrating the Role of Natural Killer Cells
A Guide to the Coronary Angioplasty Procedure
A Guide to the Coronary Angioplasty Procedure
Pathologic Myopia
Pathologic Myopia
Ventilator Associated Pneumonia (VAP)
Ventilator Associated Pneumonia (VAP)
An Animation of The Hepatitis C Virus and How it Affects the Body
An Animation of The Hepatitis C Virus and How it Affects the Body
A National Geographic Film on the Spread of the Flu Virus
A National Geographic Film on the Spread of the Flu Virus
Does chronic venous insufficiency play a role in MS pathogenesis? Commentary (CONy 2010)
Does chronic venous insufficiency play a role in MS pathogenesis? Commentary (CONy 2010)
Rivaroxaban vs enoxaparin for the Prevention of Venous Thromboembolism
Rivaroxaban vs enoxaparin for the Prevention of Venous Thromboembolism
Belimumab MOA in Systemic Lupus Erythematosus
Belimumab MOA in Systemic Lupus Erythematosus
Urethroplasty For A Rare Case Of Traumatic Adult Hypospadias
Urethroplasty For A Rare Case Of Traumatic Adult Hypospadias
A Step-by-Step Guide to Western Blotting
A Step-by-Step Guide to Western Blotting
Discussion of Clinical Approach to Lower Back Pain
Discussion of Clinical Approach to Lower Back Pain
How Flu Attacks the Human Body - An Animation
How Flu Attacks the Human Body - An Animation
An Animation Explaining the Mechanisms Involved in Hereditary Spherocytosis
An Animation Explaining the Mechanisms Involved in Hereditary Spherocytosis
The Mechanism of Natural Killer Cells in Preventing Metastasis and Inducing Apoptosis
The Mechanism of Natural Killer Cells in Preventing Metastasis and Inducing Apoptosis
Autoimmune Diseases that Affect Women-Anti-phospholipid Syndrome
Autoimmune Diseases that Affect Women-Anti-phospholipid Syndrome
A Discussion of theRole of a Family Physician
A Discussion of theRole of a Family Physician
Robotic Laproendoscopic Single-Site Radial Prostatectomy Surgery
Robotic Laproendoscopic Single-Site Radial Prostatectomy Surgery
An Insight into the Link Between ADHD and Sleep Disorders
An Insight into the Link Between ADHD and Sleep Disorders
Surviving Sepsis Campaign Guidelines 2012
Surviving Sepsis Campaign Guidelines 2012
An Animation Explaining the Development of Lymphoma
An Animation Explaining the Development of Lymphoma
An Overview of Post-Operative Pain Management
An Overview of Post-Operative Pain Management
The Prevention and Treatment of Obesity
The Prevention and Treatment of Obesity
Does chronic venous insufficiency play a role in MS pathogenesis? Commentary (CONy 2010)
Does chronic venous insufficiency play a role in MS pathogenesis? Commentary (CONy 2010)
Discussion of Systemic Candida and Yeast Infections
Discussion of Systemic Candida and Yeast Infections
Advances in Dual Antiplatelet Therapy for Acute Coronary Syndrome (ACS)
Advances in Dual Antiplatelet Therapy for Acute Coronary Syndrome (ACS)
Surviving Sepsis Campaign Guidelines 2012
Surviving Sepsis Campaign Guidelines 2012
An Animation of The Main Roles of the Immune System
An Animation of The Main Roles of the Immune System
Traditional Chinese Medicine - An Overview of Acupuncture, Meridians and Chi
Traditional Chinese Medicine - An Overview of Acupuncture, Meridians and Chi
A Discussion of Sleepwalking in Children
A Discussion of Sleepwalking in Children
Discussion of a Paper that found Tumor-Derived Vaccine Improves Survival in Follicular Lymphoma
Discussion of a Paper that found Tumor-Derived Vaccine Improves Survival in Follicular Lymphoma
An Introduction to Diagnosing Gastroschisis or Omphalocele
An Introduction to Diagnosing Gastroschisis or Omphalocele
Ventilator Associated Pneumonia (VAP)
Ventilator Associated Pneumonia (VAP)
Flash Lecture: Changes in Antithrombotic Use
Flash Lecture: Changes in Antithrombotic Use
An Overview of the Current Advances in Radiology
An Overview of the Current Advances in Radiology
An Overview of Brain Surgery and the Current Understanding of Brain Function
An Overview of Brain Surgery and the Current Understanding of Brain Function
An Update to the use of Vaccines in Patients with Chronic Medical Conditions
An Update to the use of Vaccines in Patients with Chronic Medical Conditions
Isolated Intestine and Colon Transplant - 10 Year Old Male with Tufting Enteropathy
Isolated Intestine and Colon Transplant - 10 Year Old Male with Tufting Enteropathy
Ask The Geriatrician - The Physiology of Ageing
Ask The Geriatrician - The Physiology of Ageing
A Journey Through the Immune System - in healthy individuals and during diseases.
A Journey Through the Immune System - in healthy individuals and during diseases.
An Animated Explanation of Hallux Limitus and Hallux Rigidus
An Animated Explanation of Hallux Limitus and Hallux Rigidus
A Discussion on How Drugs for RA and Psoriasis May Cut Diabetes Risk
A Discussion on How Drugs for RA and Psoriasis May Cut Diabetes Risk
Demonstration of a Shield Graft & Alar Rim Graft Surgery
Demonstration of a Shield Graft & Alar Rim Graft Surgery
A Guidance for Administration of Local Epidural Anaesthetic
A Guidance for Administration of Local Epidural Anaesthetic
The WHO Strategy to Combat Neglected Tropical Diseases
The WHO Strategy to Combat Neglected Tropical Diseases
An Overview of COPD; Symptoms, Diagnosis and Treatment
An Overview of COPD; Symptoms, Diagnosis and Treatment
Achondroplasia
Achondroplasia
An Introduction to Thrombosis
An Introduction to Thrombosis
Presentation on Torso Trauma From the Emergency Medicine and Trauma Update 2010
Presentation on Torso Trauma From the Emergency Medicine and Trauma Update 2010
Treatment and Surveillance of Non-Muscle Invasive Bladder Cancer - Part 1
Treatment and Surveillance of Non-Muscle Invasive Bladder Cancer - Part 1
The Benefits of Early Mobility in the ICU
The Benefits of Early Mobility in the ICU
Ayurveda - How Integrating this Ancient Practice Can Improve Health and Wellbeing
Ayurveda - How Integrating this Ancient Practice Can Improve Health and Wellbeing
Ventilator Associated Pneumonia (VAP)
Ventilator Associated Pneumonia (VAP)
A Discussion of Interventional Cardiology and the Procedures Involved
A Discussion of Interventional Cardiology and the Procedures Involved
Posterior Vitreous Detachment
Posterior Vitreous Detachment
Lung Transplants - The Benefits and Limitations
Lung Transplants - The Benefits and Limitations
Clostridium difficile: Community and Healthcare Associated Infections
Clostridium difficile: Community and Healthcare Associated Infections
Laboratory Investigations Involved in the Diagnosis and Treatment of Fungal Infections
Laboratory Investigations Involved in the Diagnosis and Treatment of Fungal Infections
Treatment and Surveillance of Non-Muscle Invasive Bladder Cancer - Part 2
Treatment and Surveillance of Non-Muscle Invasive Bladder Cancer - Part 2
A Guide to Taping a Foot Arch for Support
A Guide to Taping a Foot Arch for Support
An Overview of Techniques Involved in Gynaecological Surgeries
An Overview of Techniques Involved in Gynaecological Surgeries
Diabetic Macular Edema
Diabetic Macular Edema
Diabetic Macular Edema
Diabetic Macular Edema
Prostate Cancer
Prostate Cancer
Tocilizumab for the Treatment of Rheumatoid Arthritis
Tocilizumab for the Treatment of Rheumatoid Arthritis
An Animation Explaining Claw Toe
An Animation Explaining Claw Toe
An Animation of How the HPV Virus Works
An Animation of How the HPV Virus Works
Optic Nerve Hypoplasia Update - February 2011 UCSD
Optic Nerve Hypoplasia Update - February 2011 UCSD
Diabetic Peripheral Arterial Disease (P.A.D.)
Diabetic Peripheral Arterial Disease (P.A.D.)
A Presentation on Providing Quality of Care at the End of Life
A Presentation on Providing Quality of Care at the End of Life
An Introduction to Genetics and Genetic Testing
An Introduction to Genetics and Genetic Testing
A Presentation on the Advances in Paediatric Cardiology
A Presentation on the Advances in Paediatric Cardiology
The Lead: Time to Abandon LDL Treatment Targets?
The Lead: Time to Abandon LDL Treatment Targets?
Transversus Abdominis Plane (TAP) Scanning Demonstration
Transversus Abdominis Plane (TAP) Scanning Demonstration
An Animation Explaining the Development of Lymphoma
An Animation Explaining the Development of Lymphoma
Onychomycosis
Onychomycosis
Achondroplasia
Achondroplasia
An Animated Explanation of the Causes of Bunion Pain and Hallux Abducto Valgus Surgery
An Animated Explanation of the Causes of Bunion Pain and Hallux Abducto Valgus Surgery
Advances in Dual Antiplatelet Therapy for Acute Coronary Syndrome (ACS)
Advances in Dual Antiplatelet Therapy for Acute Coronary Syndrome (ACS)
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
Complementary And Alternative Medicine
Complementary And Alternative Medicine
Rheumatoid arthritis: Rheumatoid arthritis is a progressive disease that affects over 350,000 people in the UK.
Rheumatoid arthritis: Rheumatoid arthritis is a progressive disease that affects over 350,000 people in the UK.
Early rheumatoid arthritis diagnosis: Getting a referral to a Rheumatologist is critically important at the first symptoms or signs of Rheumatoid Arthritis.
Early rheumatoid arthritis diagnosis: Getting a referral to a Rheumatologist is critically important at the first symptoms or signs of Rheumatoid Arthritis.
Eribulin Trial Success
Eribulin Trial Success
Coping with arthritis
Coping with arthritis
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
A Description of TIME Wound Assessment and Treatment Strategies
A Description of TIME Wound Assessment and Treatment Strategies
What is arthritis?
What is arthritis?
Treatments for arthritis: Learn what kinds of medications are most effective for the treatment of arthritis and what other things you can do to help relieve tour pain.
Treatments for arthritis: Learn what kinds of medications are most effective for the treatment of arthritis and what other things you can do to help relieve tour pain.
Surviving Advanced Breast Cancer
Surviving Advanced Breast Cancer
The Dynamics of Thrombin and Platelet Activation in Thrombosis and Inflammation on Vimeo
The Dynamics of Thrombin and Platelet Activation in Thrombosis and Inflammation on Vimeo
Physiotherapy and osteoarthritis: The main issues with osteoarthritis are both pain and stiffness, and physiotherapy can help with both.
Physiotherapy and osteoarthritis:  The main issues with osteoarthritis are both pain and stiffness, and physiotherapy can help with both.
A Description of TIME Wound Assessment and Treatment Strategies
A Description of TIME Wound Assessment and Treatment Strategies
An Overview of Pancreatic NET and the Available Treatments
An Overview of Pancreatic NET and the Available Treatments
An Explanation of the Treatments Available for Advanced and Secondary Cancers
An Explanation of the Treatments Available for Advanced and Secondary Cancers
A Description of TIME Wound Assessment and Treatment Strategies
A Description of TIME Wound Assessment and Treatment Strategies
New Developments in the Treatment of Breast Cancer
New Developments in the Treatment of Breast Cancer
Hypnotherapy And The Virtual Gastric Band
Hypnotherapy And The Virtual Gastric Band
What GPs Should Know About Complementary And Alternative Medicine
What GPs Should Know About Complementary And Alternative Medicine
An Overview of Clinical Trials for Breast Cancer
An Overview of Clinical Trials for Breast Cancer
New Developments in the Treatment of Breast Cancer
New Developments in the Treatment of Breast Cancer
An Overview of Clinical Trials for Breast Cance
An Overview of Clinical Trials for Breast Cance
The Risks Of Complementary And Alternative Medicine
The Risks Of Complementary And Alternative Medicine
Lingual Brace Certification And Training
Lingual Brace Certification And Training
An Explanation of the Treatments Available for Advanced and Secondary Cancers
An Explanation of the Treatments Available for Advanced and Secondary Cancers
An Overview of Clinical Trials for Breast Cancer
An Overview of Clinical Trials for Breast Cancer
An Overview of Pancreatic NET and the Available Treatments
An Overview of Pancreatic NET and the Available Treatments

Clinical Guidelines

Diagnosis and management of acute graft-versus-host disease

Apr 2012

A joint working group established by the Haemato-oncology subgroup of the British Committee for..

... Standards in Haematology (BCSH) and the British Society for Bone Marrow Transplantation (BSBMT) has reviewed the available literature and made recommendations for the diagnosis and management of acute graft-versus-host disease. This guideline includes recommendations for the diagnosis and grading of acute graft-versus-host disease as well as primary treatment and options for patients with steroid-refractory disease. The goal of treatment should be effective control of graft-versus-host disease while minimizing risk of toxicity and relapse.

ESC Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery

Jan 2009

The present guidelines focus on the cardiological management of patients undergoing non-cardiac..

... surgery, i.e. patients where heart disease is a potential source of complications during surgery. The risk of perioperative complications depends on the condition of the patient prior to surgery, the prevalence of co-morbidities, and the magnitude and duration of the surgical procedure.

Clinical Trials

Evaluation of a Standardized Protocol for Dose Reduction in Patients With Spondylarthropathies and Clinical Remission With Anti-TNF Therapy

17-05-2012

The purpose of this study is to demonstrate that patients with Spondylarthropathies in remission under antiTNF therapy, can maintain the remission with a maintenance dose inferior to the currently recommended dose schedule.

Radiofrequency Ablation Versus Hepatic Resection for the Treatment of Hepatocellular Carcinomas Smaller Than 2 cm

06-05-2011

Recently, a clinical trial has shown that PRFA is as effective as HR for small HCC in terms of overall survival and disease-free survival. This has prompted some authors to suggest that PRFA could be more suitable than HR for early stage HCC. Some authors also have suggested that PRFA can be considered the treatment of..

... choice for patients with single HCC ≤ 2.0 cm, even when HR is possible. On the other hand, some tumors (subcapsular location, adjacent to intestinal loops or main bile ducts) may be unsuitable for PRFA because of the risk of bleeding, tumor seeding, bile leakage, perforation, and so on. Furthermore, in our previous experience, some tumors (with deep locations, which were included as "central HCC") may be also unsuitable for HR because of risks of more injury of normal liver tissue, blood loss after resection, and so on. Therefore, the appropriate therapeutic option for these HCC tumors ≤ 2 cm, especially for central HCC, is still under debate. To clarify this issue, the investigators conducted a study that included a consecutive series of patients with single resectable HCC < 2.0 cm in diameter, who underwent PRFA or HR.

Medical Journal Abstracts

Lactococcus lactis NCC 2287 Alleviates Food Allergic Manifestations in Sensitized Mice by Reducing IL-13 Expression Specifically in the Ileum

Clinical and Developmental Immunology
Jul 1905

Objective. Utilizing a food allergy murine model, we have investigated the intrinsic antiallergic potential of the Lactococcus lactis NCC 2287 strain. Methods. BALB/c mice were sensitized at weekly intervals with ovalbumin (OVA) plus cholera toxin (CT) by the oral route for 7 weeks. In this model, an oral challenge..

Is less clinical research being published by surgeons in the United Kingdom?

The Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
Nov 2010

Introduction: Concerns about the decline of surgical research have been expressed in parallel to the debate on the future of academic surgery in the United Kingdom. The aim of this study was to survey the output of UK surgeons in ten high impact general surgical journals between 1987 and 2009 to estimate whether less..

Recent Drug Updates

AZOPT

13-06-2013

To decrease elevated intraocular pressure in ocular hypertension and open-angle glaucoma. As monotherapy in patients unresponsive to beta-blockers or patients in whom beta-blockers are...

Avamys

13-06-2013

Adults, adolescents (12 years and over) and children (6 – 11 years) Avamys is indicated for the treatment of: • the symptoms of allergic rhinitis...

Omacor

13-06-2013

Post Myocardial Infarction Adjuvant treatment in secondary prevention after myocardial infarction, in addition to other standard therapy (e.g. statins, anti-platelet medicinal products, ...

Social Media

‘The Good Patient Syndrome’ - a real phenomenon?

on doc2doc

... blog: ‘Living With Cancer: The Good Patient Syndrome’ http:/well.blogs.nytimes.com/2013/01/24/living-with-cancer-the-good-patient-syndrome ...

Frailty. Is it an important clinical syndrome?

on doc2doc

Frailty. Is it an important clinical syndrome? There's a lot of talk about frailty and our local hospital has even developed a 'frailty unit' attached ...

What's the most ridiculous rule your hospital has enforced?

on doc2doc

What's the most ridiculous rule your hospital has enforced? The Trust, seeking to save money, rescinded the arrangement by which milk and coffee ...

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